Question Raiser...

1. Do we (humans) have Restriction Endonuclease?

In September 1986, Pubmed journal showed the evidence that there is Restriction Endonuclease present in humans. The presence of HsaI was identified. It was isolated from human embryo using tissue and cell extracts. The authors are Lao W.D. and Chen S.Y. It was found to be a TypeII and similar to EcoRI, although functionally differed. But till now nothing more is known about these HsaI enzyme.

2.Do Apoptosis occur in Bacteria?

As a function of Programmed cell death the bacteria die giving rise to newer cells either by spore formation or fruiting bodies. The cell death of bacteria is a fate of it written at genome level. Hence it is necessary for developmental stages, newer cell growth and increase in population.It also doesn't hamper other cells surrounding it, which proves another criteria.We can call it Apoptosis. 

Question Raiser

It has been all day long I was thinking of being myself as a CELL. Do you know we can call ourselves as a cell, well may be surely Diploid. Once in our lifetime with lowest cell density and volume although ratio may vary compared to now, we were formed. Thanks to those Cells who fused with an energy that can change the world and the Fusion product is finally You.
Why not we determine ourselves as those cells and having the Potential Energy within us to derive more meaningful way of life though neighboring cells exist to compete with us.
Okay. Let's Raise a question. Obvious fro the fact that we know something and is not clear will be questioned always.

1.Why don't we(Humans) have Restriction-Modification System?
Being a single celled bacteria are invaded by virus by the genetic material directly and needs an immediate restriction system and even to protect itself from the foreign genetic composition.
Whereas in humans, we have a higher organisation and the virus invasion occurs as whole virus entering our body. Hence there are other cell types(like macrophages) and specifically cell surface markers even to detect them. And hence we developed the so called Higher Version of RM system as Immune System.

And also we are prone to invasion by pathogens like bacteria, protozoans, worms and hence we need a flexible system to carry out restrictions for all these organisms.
May be true for instance.
It raises another Question :

2.Do the bacteria are invaded ONLY by viruses?
Certainly No. As there is a sole evidence of the antibiotic Penicillin from Penicillium rubens fungi causing the death of Staphylococci and Streptococci bacteria. The fungi was used by A. Fleming.
Hence may be there are other invading organisms although through chemical entities those can kill the bacterial cells. Why it is important to know is the chemical nature of peptidoglycan layer keeps it a secret.

A bio-Hypothesis

MY   PRESUMED   HYPOTHESIS

   “The only truth is death.”           

        Yet it’s true. The BIRTH is the interesting fact in all the time science has revealed and spiritually we are the GOD’s creation. And more interesting one is the DEATH. Basically we die just our time ends and our soul is being taken by the creator as the spiritual human believes. Science gives it a solution although particular proof does not exist. Scientifically the presence of soul has been proved by the scientists. A fact I am going to disclose before you might be absurd to hear but is a fact. A body just before some hours of his death was accidentally weighed for some medical tests. And he was sealed in a glass chamber for respective treatment and fully equipped. But he could not pass the treatment and died. The weight found to be exactly some 0.221g less than the original weight recorded before. Also there was a crack on the glass chamber. However may be it was electric, scientific or situation but for that moment it is presumed that the soul has been taken out of the body. It can also be explained as the metabolism and activities stopped and he died so the weight is lost. Then again a question arises why the glass was found broken in which the body was sealed?

“The sky is the daily bread of life.”

Why we take food and nutrition? The answer lies within the cells. The cells contain proteins, enzymes, fluids, genetic materials for our growth and development. But all are not available in the cells as we think. So to provide the cells their required enzymes, factors and nutritional substrates we are bound to eat. If we don’t eat or drink the body may exist on the things it has itself in the cells and will end our metabolism at finishing point. Then another question comes to mind even we take sufficient food and nutrition how we get old and why do we die?

      Ok leave it as a question unanswered. Now a very interesting truth I am disclosing about the BIRTH and DEATH. At the time of our formation by our parental gametes all is decided in our genes before we take birth and could see the sunlight. The genes as we know encode for certain functions in our body as protein synthesis. A basic concept lies in the chromosome rather a full matured chromosome. The telomeric sequence not the whole of two ends but only the one end of the chromosome contains the desired functional genes determining our age (although junk DNA is also replicated along with functional genes). The each replication of DNA , then its translation and the protein synthesis shortens some portion of the genes encoding our age. At the time of our birth we have been supplied with a variable number of functional genes for our extent of activities with respect to time different in different individual. As we grow our genes required for determination shortens but is negligible as compared to the replication process and we are called young at that certain period. But due to continuous removal of telomeric age determining genes we lose our efficiency to synthesize the required metabolic pathways for our body. And after certain years of passage almost all of our synthesizing genes for age determination ends and we have close our genomic activities which leads to the inability of the parts our body one by one and lastly stops at the eyelid. We have fixed time on this earth naturally. And all we have to use the time fully we have got in our genes. As a biotechnology learner and a human being I must tell the world not to make the stress out of any reason. The stress, tension, anger, sadness etc. will not be productive for our genes for the synthesis of desired protein, rather are the mutational factors to bring out our sudden collapse and death. We are not afraid of DEATH but certainly afraid of its way. So let it be in its way. The fact I have told you is a recently discovered truth about our genes specifically chromosomes. The longer the telomeric region longer will be the age of that individual. Yet another chapter is to be unfolded by the biotechnological research in space-biotechnology for the research of living matters like DNA in space.

“Something what we tell is already being told.

But today there is none to listen to them.”

 

 Another unanswered question remains as itself is that does the DNA exists even after we die and if yes where does it goes? Obviously the answer is yes the DNA exists in certain amounts after we die and also after the body is being burnt into ashes. My presume states a greater look into these facts biotechnologically will make us sure about them. Think about the fact strongly that we are diploid cells. And say to yourself “I am a diploid cell.” we have grown in the cytoplasm of environment and protoplasm of air. Yet we still fight for our existence. It’s very strange. Science and spiritual necessities can make us to discover new spectra of facts.

And I will tune as follows:

“A little pain, a little pleasure

A little heaping up of treasure

Then no more gazing upon the sun

All things must end that have begun.”

A fervour flamboyant detour waits for us far out at the beds of red Georgia hills and blade of grasses labeled with fluorephores  of our agile heresy.